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Generally, the most delicate moment during neural tube formation is the closure, which may result in NTDs, like spina bifida or anencephaly, if not properly regulated [18]

Cameron AD, Sinning I, LHermite G, Olin B, Board PG, Mannervik B, et al

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Eating large amounts of food at once can put a strain on the body and trigger seizures

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In response to increased plasma Hcy concentrations, there may be vascular endothelial dysfunction, reduced expression of thrombomodulin and activated protein C [64], a decrease in the presence of anticoagulant heparans [65], and a decrease in tissue plasminogen activator receptors on the surface of vascular endothelial cells [66]