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Predicted human DAT structure are colored light gray

de Beeck, K

This suggests that the compounds exhibited strong binding affinities with the target proteins

Modulation of -glutamylcysteine synthetase large subunit mRNA expression by butylated hydroxianisole

Potency refers to how strong the peptides effect is at a given dose

Given that the cellular thiol network, including GSH, involves crosstalk between the cytosol and organelles, we selected two of the dysregulated enzymes, which had been identified by 2D electrophoresis, with important roles in mitochondrial function, i.e., Aco2 and mitochondrial creatine kinase (mtCK) (Fig