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604 Granulathiazole A increases the expression of FSP1, GPX4, SLC7A11, while lowering ACSL4 levels by activating the Nrf2/HO-1 pathway, improving the accumulation of -synuclein

g , GGT1 mRNA expression levels in human tumoral and non-tumoral tissues from the Cancer Genome Atlas Program (TCGA) and the Genotype-Tissue Expression (GTEx) databases

The typical presentation of holocarboxylase synthetase deficiency is seen in the neonatal period with onset occurring within hours to weeks of birth

Although direct interconnections between the release of pro-inflammatory cytokines and S accumulation have yet to be established, altered pro-inflammatory cells in experimental PD models suggest that inflammation and S dysregulation are closely interconnected (Tan et al., 2020)

Mitochondrial dysfunction in Alzheimers disease and the rationale for bioenergetics based therapies