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Phosphorylation of GCLC was also demonstrated in cultured hepatocytes after treatment with dibutyryl cAMP (DBcAMP) or phenylephrine using specific antibodies which immunoprecipitated the phosphorylated GCLC

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Treatment Vitamin B12 is administered via injection in the office

This hypothesis is supported by the fact that these changes are only observed in cells under continuous treatment and not the other cell lines
