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Description
Deficiency in holocarboxylase synthetase is an autosomal recessive disorder that results in deficiency in all four biotin-dependent carboxylases
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Although originally described as an ATP-dependent enzyme, recent work has demonstrated that TPK1 can utilize several nucleotides as phosphate donors for the phosphorylation of thiamine
Hassan, Abeer A
PubMed Central , The Journal of Nutrition, Health & Aging , vol
The use of antipsychotic drugs relieves these symptoms to some extent [119], but they can also lead to several side effects, such as metabolic syndrome and weight gain [120,121]
