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It is of some interest that realgar, a polymorph of arsenic sulphide (As 4 S 4 ), and cinnabar (mercury sulphide) found an ethno-pharmacological use in Chinese medicine [193,194]

Where serum B12 results are borderline or do not fit the clinical picture, further tests such as active B12 (holotranscobalamin), methylmalonic acid, or homocysteine may be helpful

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Chronic anemia also increases the risk of leg ulcers and thrombotic events, including pulmonary embolism and portal vein thrombosis, particularly in patients post-splenectomy

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