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Specifically, KYN primarily restores the diversity of the gut microbiota, whereas ILA and I3C markedly enhance the proliferation of bacteria associated with tryptophan metabolism, such as Akkermansia and Ruminococcus_1

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These results provide further evidence that crocin attenuates oxidative injury and inflammation in HNEpCs through the KEAP1-NRF2/HO-1 pathway