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Description
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In particular, ageing is followed by significant modifications in the hepatic CYP isozyme expression pattern in humans, which are CYP isozyme-specific (102) and these modifications can affect drastically the oxidative biotransformation of the majority of drugs in the market, and numerous other xenobiotics including environmental pollutants, pre-carcinogens, carcinogens, and toxicants along with the biosynthesis of several endogenous compounds (101, 102)
Complexation of this scaffold with transition metals produced substantial improvements in the biological potential
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Knocking out OSMR in sensory neurons or systemic administration of gp130 inhibitors suppresses inflammatory itch in mice (42)
Arch Pharm (Weinheim) 349:507522
