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43 However, the Streptomyces spp and lactic acid bacteria are probably more prominent in antioxidant production

Mechanistically, phenotypic heterogeneity may arise from factors such as uneven division of cells and their constituents, heterogeneous stages of the cell cycle or cell ageing, epigenetic modifications and stochastic gene expression [111314]

DeBerardinis RJ, Mancuso A, Daikhin E, Nissim I, Yudkoff M, Wehrli S, Thompson CB: Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

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In contrast, its use in specific clinical contextssuch as circadian rhythm sleep disorders, neurodegenerative diseases, or metabolic dysregulationis addressed as an adjunctive therapeutic approach, where evidence remains heterogeneous and often limited to small-scale or short-term studies