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In experimental models of cerebral ischaemia, DSIP administration was associated with accelerated restoration of motor coordination and reduced neuronal damage, with proposed mechanisms involving stabilisation of neuronal membrane function and protection against excitotoxicity from excessive glutamate signalling

47 They found that when drugs are administered intranasally, the use of nanoformulations significantly increases DTE and DTP values compared to when drugs are in solution form, demonstrating the advantages of nanoformulations in intranasal administration

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Alternatively, a BPC-157 dosage of 400600 mcg/day has proven to be effective when administered via subcutaneous injection in close proximity to the affected region

A once-daily topical spray is far more accessible than clinical microneedling procedures