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Description
Nature Reviews Neuroscience, 13(5), 293307
The FDA has approved the use of L-carnitine (by mouth or intravenously) treating L-carnitine deficiency caused by certain genetic diseases, end-stage kidney disease, and other disorders
Intracellular metabolite concentrations have to fine-tune the signaling networks governing metabolic pathways independently of the environment to ensure a balance between the availability of nutrients and the cellular capacity to use them effectively
Once done, they can be made available for use as energy
The rapidly acting antidepressant ketamine and the mGlu2/3 receptor antagonist LY341495 rapidly engage dopaminergic mood circuits
10.2307/3801655 27 CasaschiA.RubioB
