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McCluggage WG, Maxwell P, Hamilton PW, Jasani B

The British Journal of Nutrition, 108 (6), 984997

Clinical studies indicate that rosuvastatin reduces urinary IL-6 and CD40 ligand levels in patients with DKD, correlating with a reduction in macrophage density in renal biopsies (123)

In addition, cystamine abrogated BSO-induced increase in total and dimeric iNOS proteins (Fig

doi: 10.1172/JCI44478

This is totally dependent upon increased function of adhesion molecules expressed both on the surface of inflammatory cells and on the surface of kidney tissue
