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the KISS1 gene product, available as kisspeptin-10 or kisspeptin-54) is a naturally occurring neuropeptide that stimulates hypothalamic GnRH neurons to drive release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) [1] [5]

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Untreated hypogonadism and testosterone replacement therapy in hypogonadal men are associated with a decreased risk of subsequent prostate cancer: a population-based study