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Dietary copper and human health: current evidence and unresolved issues

Subependymal giant cell astrocytomas are often associated with TSC1 and TSC2 mutations

Accumulation of -syn as intracellular filamentous aggregates is a pathological feature of both sporadic and familial PD ( DJ-1 is another gene reported to cause a familial early onset PD ( Neuroinflammation Neuronal loss in PD is associated with chronic neuroinflammation, which is controlled primarily by microglia, the major resident immune cells in the brain ( -syn or LRRK2 ( Neuromelanin confers the dark pigmentation that is produced from DA oxidation and is so characteristic of the SNpc appearance

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The SDMT score correlated positively with the levels of 4-HNE ( r = 0.312, p = 0.022) and negatively with the levels of TAC ( r = -0.285, p = 0.015) (Fig
