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In AD models, it decreases astrocyte activation through JAK2/STAT3 pathway inhibition, requiring careful dose control to preserve neuronal viability (275)

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DLD1 is heterozygous for S241F TP53 mutation, which is a non-functional mutation

In fact, 40 percent of the cancer cases diagnosed in the United States in 2014 were caused by potentially modifiable risk factors (46)

Regulation of cortisol levels - considered a potential modulator of stress response and homeostasis

Musa, J