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Q.YangY.-P.ChouS.-J.et al (2020)

Importantly, overexpression of MSI1 weakened the antitumor effects of miR-769-5p, affirming its role as a downstream effector (46)

In LPS-stimulated BV-2 microglial cells, ISA can activate the GSK-3 and its downstream Nrf2 and HO-1, which suppressed the activation of NF-B and the subsequent production of inflammatory mediators, causing the inhibition of inflammation (Wang et al., 2018a)

So NACs timing isnt arbitrary

We have air filters

Studies have shown that andrographolide can be used to treat inflammatory lesions of various systemic diseases
