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[138] demonstrated that the expansion of immunosuppressive cells in brain reduced the efficacy of immunotherapy for glioblastoma in elderly patients
It is not just the load -- it is the combination of load, volume, and variety
Cancer Cell (2017) 31(4):563575 e565
This neurotoxic environment is believed to be a primary driver of the debilitating cognitive dysfunction, or 'brain fog,' that patients experience daily
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[55] however, tumors also exploit this effect to protect themselves against oxidative stress
