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The product is likewise indicated for increased physiologic demand (pregnancy, thyrotoxicosis, chronic hemorrhage), for drug-induced depletion, and for select neurologic or hematologic disorders in which B12 plays a pivotal metabolic role

Researchers usually select this material when a defined compound or peptide profile is needed for repeatable assays, comparison studies, or exploratory pathway research

Limited value of serum holo-transcobalamin II measurements in the differential diagnosis of macrocytosis

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The British Society for Haematology emphasises that treatment should not be delayed whilst awaiting confirmatory test results if clinical suspicion of B12 deficiency is high, particularly when neurological symptoms are present

To summarize, this is a report of a case of severe progressive systemic sclerosis in a forty-nine year old white female, who was in good health two years prior to being seen in Dr