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The human leptin mutants K33A/Q34A/K35A (KQK-AAA) and S117N displayed partial agonism of human LepR, with maximal STAT3 responses of approximately 75% and 45% of WT leptin, respectively (Fig

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Discussion Myeloid mimicry induced by IFN signaling was recently described as a mechanism of immune evasion in mouse models of glioblastoma multiforme 41

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Macrophages regulate the inflammatory process depending on their differentiation status

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