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This precise temperature drop is a deeply ingrained evolutionary signal that it is safe to initiate sleep

10.2147/NSS.S134864 [DOI] [PMC free article] [PubMed] [Google Scholar] Mezhnina V, Ebeigbe OP, Poe A, Kondratov RV (2022) Circadian control of mitochondria in reactive oxygen species homeostasis

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The percentage of 5-mC was calculated using the second-order regression equation of the standard curve constructed with the negative and positive controls

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