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[] When treating ulcerative colitis from the perspective of the liver, Tong-Xie-Yao-Fang () was the classic prescription for painful diarrhea by nourishing the spleen and clearing heat in the liver (), Si-Ni-San, Xiao-Yao-San, and Chai-Hu-Shu-Gan-San with Shen-Ling-Bai-Zhu-San () as a combined formula were used for soothing the liver and regulating the spleen ()