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Overall, the monomer can have marked proinflammatory properties both in vitro and in vivo as it promotes monocyte chemotaxis and their recruitment, along with the recruitment of circulating leukocytes to the inflammation areas through FcRI and FcRIIa signaling, whilst also causing them to form ROS [80]

In Genet

Published 2010 Apr 16

Sustained UPR can promote the development of MAFLD by regulating lipogenesis, causing inflammation, and inducing hepatocyte death (Lebeaupin et al., 2018

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