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doi: 10.1096/fj.00-0802com 76 AttoubSRivatCRodriguesSVan BocxlaerSBedinMBruyneelEet al
Hydroperoxide levels, in particular, are cause for concern if the reaction involves an oxidation prone drug substance, and if the formulation is destined for a parenteral route of administration (81)

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doi: 10.1016/j.jcv.2012.12.020

& Rodrigues, R

mTOR and HDAC inhibitors converge on the TXNIP/thioredoxin pathway to cause catastrophic oxidative stress and regression of RAS-driven tumors