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Biomarkers of immune activation such as NK cell activity, CD8 + T cell infiltration, cytokine profiles (IL-12, IFN- and IL10), and Treg/MDSC ratios help identify populations of patients likely to benefit from immunomodulatory agents whereas circulating levels of polyphenols, isoflavones or glucosinolate metabolites serve as a marker for PK properties that can be utilized to optimize dosing and exposure (224)

Redox Biol (2020) 32:101483

doi:10.1073/pnas.90.2.770

[ 3 H]BPC157 was rapidly metabolized into a variety of small peptide fragments in vivo , thus forming single amino acids that entered normal amino acid metabolism and excretion pathways

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Future work may explore metabolically informed dietary personalization, including the role of medium-chain fatty acids such as decanoic acid (C10), which has demonstrated neuroactive and antiseizure properties