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Long-term safety data is limited, so caution is advised

An siRNA screen for suppressors of ferroptosis in 2016 revealed that the top hit was knockdown of CARS , the cysteinyl-tRNA synthetase, which suppressed erastin-induced ferroptosis through activating the transsulfuration pathway (Hayano et al., 2016)

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Chem 35 (1996) 44904496

Blood pressure readings higher than 180/120 mm Hg are considered dangerously high and require immediate medical attention

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