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AstraZeneca Lead assets: Elecoglipron, an oral GLP-1RA candidate Metabolic focus: Obesity, overweight, type 2 diabetes and cardiometabolic disease AstraZeneca is developing elecoglipron as a once-daily GLP-1RA pill for obesity and type 2 diabetes
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These were, i.e., in the cerebellum (ibuprofen [107], paracetamol [61]), the cerebral cortex (diclofenac [106,108], celecoxib [105]), the frontoparietal cortex (concussive brain trauma) [78], the hippocampus and the cerebral cortex (insulin) [62], and the parietal neocortex and hippocampus (cuprizone [80]) (note, cuprizone application [80] was an extremely high regimen highly over those commonly applied to mimic multiple sclerosis in rats [268,269])

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