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Furthermore, early in vitro work showed that BSPs demonstrated significant anti-inflammatory activity with inhibitory effects on the expression of IL-1, TNF-, and inducible nitric oxide synthase (iNOS) in the murine macrophage cell line RAW264.7 at a concentration of 200 g/mL (Diao et al., 2008)

The antibodies against phospho-AKT(Ser473) (4060), AKT(pan) (4691), phospho-p70S6K(Thr389) (9205), p70S6K (2708), phospho-ERK1/2(Thr202/Tyr204) (4370), ERK1/2 (4695), phospho-S6 ribosomal protein (Ser235/236) (4858), S6 ribosomal protein (2217), phospho-MDM2(Ser166) (3521), phospho-MEK1/2(Ser217/221) (9154), MEK1/2 (8727), MEK1 (12671), and cleaved caspase 3 (9664) were purchased from Cell Signaling (1:1000 or 1:2000 dilution)

View Certificate of Analysis (COA) 10mg $26.00 RETA Price range: $27.00 through $148.00 Price includes 3ml research water

Moreover, Gpx4 has been shown recently to modulate ferroptotic cancer cell death, a specific form of cell death characterized by the production of iron-dependent ROS generation (Yang et al., 2014)