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The documented effects are local skin reactions irritation and the less common allergic contact dermatitis plus the procedural risks of microneedling where it's used as a delivery aid

Published preclinical studies have investigated 5-Amino-1MQ as a selective inhibitor of Nicotinamide N-methyltransferase (NNMT) in laboratory models (Neelakantan et al., 2018)

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CD38 is a druggable target in the therapy of human cancers