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A classic antibiotic reimagined: rationally designed bacitracin variants exhibit potent activity against vancomycin-resistant pathogens

Up to a 10% to 20% weight loss, or higher, has been seen with these newer treatments, but some people need to stop treatment because of stomach side effects (nausea, vomiting, diarrhea, constipation and stomach pain)

doi: 10.1016/s0272-6386(03)00113-6

[DOI] [PubMed] [Google Scholar] 125.Hellstrom WJ, Kendirci M, Matern R, et al

There are a couple of things you can do to improve the longevity of your results, in fact, we made a video about it

Substrate binding and catalytic mechanism in phospholipase C from Bacillus cereus: a molecular mechanics and molecular dynamics study