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Description
J Lipid Res 45: 19581961, 2004
[DOI] [PubMed] [Google Scholar] 50.Forester BP, Berlow YA, Harper DG, et al

Other studies found that TMAO induces hypercholesterolemia by promoting intracellular CHO accumulationenhancing macrophage cholesterol accumulation via microbiota-dependent pathways involving the increased expression of pro-atherogenic scavenger receptor proteins CD36 and SRA on the cell surface (Wang et al., 2011)
The overexpression of the truncated SREBP2 in the liver dramatically enhances cholesterol synthesis with a modest induction of lipid synthesis (131)

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For instance, high doses of certain vitamins like vitamin A can be toxic, and some mineral supplements may interfere with absorption of other nutrients