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10.2174/1574889810999160603185126 53 CinarR.IyerM
Myeloid deficiency of Z-DNA binding protein 1 restricts septic cardiomyopathy via promoting macrophage polarisation towards the M2-subtype
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Abbreviations: GSSG, oxidized glutathione
BOX1: Complexity of genetic alterations and metabolism in PDAC In addition to the most frequent oncogenic somatic mutation KRAS , a high percentage of patients carry inactivating somatic mutations in the tumor suppressors cyclin-dependent kinase inhibitor 2 A ( CDKN2A ), tumor protein 53 ( TP53 ), and SMAD family member 4 ( SMAD4 ) [113,114,115], reinforcing their roles during PanIN-to-PDAC [116]
Koch, P., Platzer, M
