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Microneedles (MNs) represent one such innovative platform, where targeted drug distribution is made possible by MNs ability to pass through the corneas and scleras barriers, thereby enhancing therapeutic outcomes [5]

Europ Rev Med Pharmacol Sci

Gong H, Xie J, Zhang N, Yao L, Zhang Y

Melville DB, Genghof DS, Inamine E, et al

For example, pro-inflammatory factors (e.g., tumor necrosis factor- (TNF-), interleukin-1 (IL-1), and interleukin-6 (IL-6), etc.) (9295), inflammatory mediators (e.g., prostaglandins (PGE2), nuclear kappa factor B (NF-B), and cyclooxygenase-2 (COX-2), etc.) (96, 97), and oxidative stress-associated molecules (e.g., ROS, RNS, and MDA, etc.) are upregulated after stroke (98, 99)

Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II