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Chaput M., Ness B

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ArticlePubMed 43

However, whilst multiple compounds targeting redox regulation have been reported to slow disease progression in SOD1 G93A mice (Dash et al., 2018), they have subsequently failed to enhance survival or improve motor function in ALS patients in clinical trials

By inhibiting enzymes in this pathway, especially through crocin, saffron lowers the production of harmful metabolites