glutathione recycles antioxidants The antioxidant network in skin: predominant role of-tocopherol and its Vitamin C and glutathione supplementation:

This specific chemical structure acts as a potent reducing agent, allowing it to act like a cellular sponge for highly reactive, unstable molecules known as free radicals or reactive oxygen species (ROS)

Glutathionylation activates both p21ras, leading to phosphorylation of ERK and Akt as downstream targets, and ryanodine receptors, causing calcium signals that enhance ERK and CREB phosphorylation

This neutralization of free radicals and activity in the mitochondrial transport chain system can help to decrease signs of skin aging and can help regenerate skin elasticity involved in skin aging

Leaky gut and brain fog: Research supports that a leaky gut is a key component in autoimmunity, and a leaky gut is often associated with leaky brain and brain fog

Similarly to what is observed after exposure to chronic stress in mice (see discussion above), individuals with MDD present reduced spine synapses and decreased brain volume, especially in PFC and hippocampus (Hastings et al., 2004

Genes Dev 27:10161031