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In a trial trying to assess the best treatment parameters, no significant differences were observed between various energy flux density levels

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2 Among these, cold exposure and fasting are well-studied paradigms that necessitate metabolic flexibility, prioritizing fatty acid oxidation over glucose catabolism to sustain systemic energy balance while sparing glucose for obligate tissues such as the brain

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Dietary eicosapentaenoic acid supplementation accentuates hepatic triglyceride accumulation in mice with impaired fatty acid oxidation capacity