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Elevated ROS levels disrupt ovarian function, contribute to insulin resistance, and exacerbate hyperandrogenism, thereby influencing both reproductive and metabolic aspects of PCOS

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doi: 10.2337/diacare.24.2.382 Meyer C, Dostou JM, Welle SL, and Gerich JE ( 2002 )

Additionally, melatonin reduced the activities of other kinases involved in tau hyperphosphorylation, such as CDK5, through the upregulation of micro-RNAs [115]