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This toxic metabolite can be synthesized through enzymatic (methylglyoxal synthase) and non-enzymatic reactions [12]

J Physiol Pharmacol, 2013

More recently, a randomized, double-blind, 24-week cross-over trial in 63 adults suffering from migraines found that 500 mg/day of magnesium oxide was equally effective as sodium valproate for reducing the migraine frequency and duration over the eight-week treatment period (194)

It has two major splice variants, hCT(a) and hCT(b), with the second one being more prevalent [45]

This describes a situation where there is too much estrogen in your body, beyond what is considered within range (30)

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