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A 2022 systematic review and meta-analysis of 18 randomized trials including 883 hypothyroid patients and evaluating outcomes like depression, fatigue, pain, anxiety, and anger, found no statistically significant advantage of combined LT4+LT3 therapy over LT4 monotherapy on any of these psychological endpoints (42)

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MR studies found genetically predicted homocysteine was associated with lacunar stroke, but was not associated with large artery or cardioembolic stroke, supporting a causal link (347)

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Molecules and functions of Cornus officinalis bark volatiles

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Haas, and T

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Therefore, plants, especially those with high quantities and potent antioxidant chemicals, can treat oxidative stress-related diseases like diabetes mellitus

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