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Authors contributions IP: Writing of the manuscript, study design, data collection and interpretation, preparation of revisions

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Phosphorylated -catenin translocates to the nucleus, binds to TCF/LEF transcription factors, and promotes the expression of many target genes, including those involved in cell proliferation, anti-apoptosis, invasion, and angiogenesis (Fig

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(3) Peroni CN, Hayashida CY, Nascimento N, Longuini VC, Toledo RA, Bartolini P, Bowers CY, Toledo SP

Since the sulfur donors coordinating zinc in MTs are redox reactive, oxidation of the sulfur donors leads to the release of zinc, which contributes to overall intracellular zinc signaling