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By suppressing NOD-, LRR- and Pyrin domain-containing protein 3 (NLRP3) inflammasome activation, autophagy reduces the secretion of pro-inflammatory cytokines ( e.g ., IL-1, IL-18), thereby mitigating chronic inflammation

Aortic plaque-targeted andrographolide delivery with oxidation-sensitive micelle effectively treats atherosclerosis via simultaneous ROS capture and anti-inflammation

Immunohistochemistry analysis indicated that chemotherapy-resistant patients had significantly higher expression levels of NRF2, GPX4 and SOD1 in tumor tissues compared to the sensitive ones
