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Finally, the released Fe3+ is reduced to Fe2+ by ferrireductases of the STEAP protein family (12,13)

Adv Mater 2023;35(14):e2210083

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Its relative stability and resistance to enzymatic degradation under certain experimental conditions have made it an interesting compound for laboratory investigations involving peptide-mediated regenerative signaling

however, GSH levels are also influenced by agents or conditions that alter the thiol redox state, that lead to the formation of glutathione S -conjugates or complexes, and/or that disrupt the distribution of GSH among various intracellular organelles

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