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doi: 10.1016/j.jconrel.2020.07.044

Nature communications 2017;8, 15691, doi:10.1038/ncomms15691

This coordination stabilizes copper in a biologically available form, allowing it to interact with cellular targets without generating oxidative stress. The copper ion also acts as a catalytic cofactor in enzymes involved in collagen cross-linking, antioxidant defense, and wound remodeling

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Dosage ranges from 0.5 mg per day for general wellness up to 2 to 3 mg per day for wound healing