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Trimethylamine-N-oxide and cerebral stroke risk: A review
PMX500FI, a synthetic carnitine-conjugated -lipoic acid derivative, can cross the bloodretinal barrier and improve mitochondrial function [321]

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However, its metabolic conversion by gut microbiota into TMAO raises significant concerns due to the association of elevated TMAO levels with cardiovascular diseases like atherosclerosis, MI, stroke, and HF

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