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We found the structure to be very similar to the published binary complex of Pt GSTF8 with GSH (PDB 5F07) 39 at an overall root-mean-square deviation (RMSD) (C) of 0.16 (Fig

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16 The study has been approved by the ethics and research committee of the University Hospital of Guadalajara (Spain)

It is composed of hydrophobic core (2-[N,N-(diisopropylamino) ethyl] methacrylate (DIPMA) and di(ethylene glycol) methyl ether methacrylate (DEGMA) copolymer) and hydrophilic shell (poly (ethylene glycol) monomethyl ether methacrylate (PEGMA) and 2-[N,N-(dimethylamino) ethyl methacrylate (DMAEMA) copolymer) encapsulated with the NK1R antagonist aprepitant (AP)

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However, the immune response of the CNS is complex and involves a myriad of diverse cell populations such as astrocytes, microglia, macrophages, NK cells, and T and B cells (Dringen and Arend, 2025)