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07 Site nodule or irritation Rotate to a fresh quadrant for several sessions, inspect the syringe-and-needle technique, and slow the injection

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Biochem Biophys Res Commun 513, 2227

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The relevant promoter mutations were located in the tip of the 3terminal stem-loop SL1 46 and have been shown to affect negative strand synthesis by disturbing recognition of a genotype-specific sequence in the tip of SL1 by NS5B 46

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