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Gong Z, Li Q, Shi J, Wei J, Li P, Chang C-H, et al
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They occur only as a result of taking high doses of vitamin C supplements

doi: 10.1038/ki.1985.223

Tuft cells act as initiators and responders, enabling two-way communication with epithelial and immune cells, and generating feedback loops with some of the effector molecules

However, cell-to-cell epigenetic variations have been identified within homogenous cell populations, therefore DNA methylation could be considered an important factor in biological variability of malignant tumors [6, 50]