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We next sought to identify post-translational modifications (PTM)s on DLD using high-resolution proteomics and to confirm the presence of HNO-dependent PTM(s)

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Targeted CRISPR screen Targeted CRISPR screens refer to methodologies which illicit perturbations in only a subset of the genome

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Studies have shown that the NOD-like receptor thermal protein domain associated protein 3 (NLRP 3) inflammasome, in response to cerebral ischemia, is activated through the pathogen-associated molecular pattern (PAMP)/DAMP signaling pathway, which promotes the conversion of caspase-1, thereby accelerating the process of pyroptosis in neuronal cells (46)