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In the cosmetic setting, BOTOX is mainly used to decrease dynamic wrinkles created by underlying muscle activity

It is preferred over cyanocobalamin due to its longer duration of action, better retention, and lower toxicity profile

In humans, methylcobalamin functions in the folate-dependent methylation of homocysteine to methionine (Figure 22b.2) whereas 5'deoxyadenosyl-cobalamin plays a major part in the conversion of Lmethylmalonyl-coenzyme A to succinyl-coenzyme A in an isomerization reaction

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Symptoms such as muscle tremors and abnormal movements have been observed, but these effects typically resolve with appropriate management and follow-up

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