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Description

In healthy cells and organs, the reaction H 2 O 2 + GSH performs the task of signal transduction to the nucleus via the nuclear factors, finally activating or inactivating special DNA segments for the production of the cell specific proteins

Cell 143 , 10471058 (2010)

What is truly important is whether your B12 level is sufficient

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Abbreviations GSH: Glutathione BSO: L-buthionine-sulfoximine ROS: Reactive oxygen species GST: Glutathione S-transferase DEM: Diethyl maleate ITCs: Isothiocyanates GCL: Glutamate-cysteine ligase GPX: Glutamate peroxidases Fmoc: 9-Fluorenylmethyloxycarbonyl TOFMS: Time-of-flight mass spectrometry TEM: Transmission electron microscopy NPs: Nanoparticles PBS: Phosphate buffered saline HPLC: High-performance liquid chromatography LCMS: Liquid chromatography-mass spectrometry IC 50 : Half-maximal inhibitory concentration CLSM: Confocal laser scanning microscopy RhoB: Rhodamine B Fer-1: Ferrostatin-1 t-BuOOH: Tert-butylhydroperoxide DCFH-DA: 2,7-Dichlorodihydrofluorescein diacetate LDH: Lactate dehydrogenase ATP: Adenosine triphosphate GSDMD: Gasdermin D GSDME: Gasdermin E References Mo R, Gu Z