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doi: 10.3389/fcimb.2024.1328419, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 43

In CUMS animals, decreased ferritin light chain 1 and Brain-derived neurotrophic factor (BDNF) levels are observed in the proteomics of hippocampal neurons, which are associated with hippocampal neuronal survival

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Unresolved chronic inflammation during aging may serve as a pathophysiologic association which converts normal functional changes to the age-related degenerative diseases (Viola and Soehnlein, 2015)